$1.25 per shot (2 fluid ounces)
Saffron extract 0.015g
Curcumin (95%) 0.500g
Creatine monohydrate, micronized, 3.000g
No fillers, binders, flow agents, anti-clumping agents, surfactants, colloids, artificial flavors, artificial colors, or any other additives
Numerous studies including multiple randomized, double-blind, placebo-controlled trials have shown that 30mg of saffron extract daily (both petals and stigma) may be effective in reducing depression in persons with major depressive disorder, and the potency appears to be comparable to reference drugs (fluoxetine, citalopram, and imipramine). That’s not to say that the evidence is equivalent to those drugs, however. Other doses may also be effective but 30 mg of extract is the most common dose.
Studies have shown that curcumin may be more effective than placebo in reducing symptoms of depression.
Curcumin is not absorbed well by the body. Piperine increases the absorption of curcumin.
At least two studies, one of which was a randomized, double-blind, placebo-controlled trial, has shown that supplementing with acetyl-l -carnitine appeared to have a notable benefit for participants with heightened depression.
In a randomized, double-blind, placebo-controlled trial, participants undergoing a depressive episode were allocated to take 200 mg of Coenzyme Q10 or placebo daily in addition to their usual medication for 8 weeks. There appeared to be a greater reduction of the depressive episode in the Coenzyme Q10 group that was statistically significant compared with placebo.
Several studies have shown that supplementing with creatine seem to noticeably improve depression symptoms.